Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

In the past few years, continuous‐flow reactors with channel dimensions in the micro‐ or millimeter region have found widespread application in organic synthesis. The characteristic properties of these reactors are their exceptionally fast heat and mass transfer. In microstructured devices of this t...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2015-06, Vol.54 (23), p.6688-6728
Main Authors: Gutmann, Bernhard, Cantillo, David, Kappe, C. Oliver
Format: Article
Language:English
Subjects:
Channels
Chemistry, Pharmaceutical
flash chemistry
flow chemistry
Hazardous
Mass transfer
Microfluidic Analytical Techniques
microreactors
Organic chemistry
Pharmaceutical Preparations - chemistry
Pharmaceuticals
Reactors
scale-up
Synthesis
Technology, Pharmaceutical
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