Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight‐Bearing and Non–Weight‐Bearing Human Bone

We investigated mechanisms resulting in low bone mineral density (BMD) and susceptibility to fracture by comparing noncoding RNAs (ncRNAs) in biopsies of non–weight‐bearing (NWB) iliac (n = 84) and weight bearing (WB) femoral (n = 18) postmenopausal bone across BMDs varying from normal (T‐score >...

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Bibliographic Details
Published in:	Journal of bone and mineral research 2020-06, Vol.35 (6), p.1065-1076
Main Authors:	Gautvik, Kaare M, Günther, Clara‐Cecilie, Prijatelj, Vid, Medina‐Gomez, Carolina, Shevroja, Enisa, Rad, Leila Heidary, Yazdani, Mazyar, Lindalen, Einar, Valland, Haldor, Gautvik, Vigdis T, Olstad, Ole K, Holden, Marit, Rivadeneira, Fernando, Utheim, Tor P, Reppe, Sjur
Format:	Article
Language:	English
Subjects:	Biopsy Body mass index Bone and Bones Bone Density - genetics Bone mineral density Bone turnover Extracellular matrix Female Femur Fractures Fractures, Bone - genetics Hip Humans Metabolism miRNA Non-coding RNA Nucleoli Osteoporosis Osteoporosis - genetics Post-menopause Proteoglycans Quantitative trait loci RNA, Untranslated - genetics Weight-Bearing
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