The regulation of spermatogenesis by androgens

•Testosterone maintains BTB, meiosis, Sertoli–spermatid adhesion and spermiation.•Testosterone acts via classical and non-classical pathways.•Testosterone regulates PTM, Leydig, and Sertoli cells via the androgen receptor.•The combined regulation of many genes by testosterone supports spermatogenesi...

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Bibliographic Details
Published in:Seminars in cell & developmental biology 2014-06, Vol.30, p.2-13
Main Authors: Smith, Lee B., Walker, William H.
Format: Article
Language:English
Subjects:
Androgens - physiology
Animals
Blood testis barrier
Fertility
Gene Expression Regulation
Humans
Male
Meiosis
Receptors, Androgen - metabolism
Sertoli cell
Signal Transduction
Spermatogenesis
Testis
Testis - cytology
Testis - physiology
Testosterone
Testosterone - physiology
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