NF-κB in immunobiology

NF-κB was first discovered and characterized 25 years ago as a key regulator of inducible gene expression in the immune system. Thus, it is not surprising that the clearest biological role of NF-κB is in the development and function of the immune system. Both innate and adaptive immune responses as...

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Bibliographic Details
Published in:Cell research 2011-02, Vol.21 (2), p.223-244
Main Authors: Hayden, Matthew S, Ghosh, Sankar
Format: Article
Language:English
Subjects:
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Biomedical and Life Sciences
Cell Biology
Gene expression
Hematopoiesis
I-kappa B Kinase - metabolism
Immune response
Immune system
Immune System - metabolism
Immune System - physiology
Immunity, Innate
Life Sciences
NF- Kappa B protein
NF-kappa B - metabolism
NF-kappa B - physiology
Review
Reviews
Transcription factors
Transcription Factors - metabolism
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