Functions of NF-κB1 and NF-κB2 in immune cell biology

Two members of the NF-κB (nuclear factor κB)/Rel transcription factor family, NF-κB1 and NF-κB2, are produced as precursor proteins, NF-κB1 p105 and NF-κB2 p100 respectively. These are proteolytically processed by the proteasome to produce the mature transcription factors NF-κB1 p50 and NF-κB2 p52....

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Bibliographic Details
Published in:Biochemical journal 2004-09, Vol.382 (2), p.393-409
Main Authors: BEINKE, Sören, LEY, Steven C.
Format: Article
Language:English
Subjects:
Review
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