GT-Scan: identifying unique genomic targets

A number of technologies, including CRISPR/Cas, transcription activator-like effector nucleases and zinc-finger nucleases, allow the user to target a chosen locus for genome editing or regulatory interference. Specificity, however, is a major problem, and the targeted locus must be chosen with care...

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Bibliographic Details
Published in:Bioinformatics (Oxford, England) England), 2014-09, Vol.30 (18), p.2673-2675
Main Authors: O’Brien, Aidan, Bailey, Timothy L.
Format: Article
Language:English
Subjects:
Applications Notes
Clustered Regularly Interspaced Short Palindromic Repeats - genetics
Computational Biology - methods
Endonucleases - metabolism
Genetic Engineering - methods
Genome, Human - genetics
Humans
Internet
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