Distribution and expression of the aac(6′)-Im (aacA16) aminoglycoside resistance gene

Abstract Background The aac(6′)-Im (aacA16) amikacin, netilmicin and tobramycin resistance gene cassette had been circulating globally undetected for many years in a sublineage of Acinetobacter baumannii global clone 2. Objectives To identify sources for the aac(6′)-Im fragment found in A. baumannii...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 2024-07, Vol.79 (7), p.1569-1576
Main Authors: Harmer, Christopher J, Nelson, Messiah J, Lebreton, Francois, Lertsethtakarn, Paphavee, McGann, Patrick T, Hall, Ruth M
Format: Article
Language:English
Subjects:
Acetyltransferases - genetics
Acinetobacter baumannii - drug effects
Acinetobacter baumannii - genetics
Amikacin - pharmacology
Aminoglycosides - pharmacology
Anti-Bacterial Agents - pharmacology
Bacterial Proteins - genetics
Drug Resistance, Multiple, Bacterial - genetics
Enterobacter - drug effects
Enterobacter - genetics
Genome, Bacterial
Humans
Integrons - genetics
Microbial Sensitivity Tests
Original Research
Plasmids - genetics
Thailand
Tobramycin - pharmacology
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