Rapid fabrication of biomimetic PLGA microsphere incorporated with natural porcine dermal aECM for bone regeneration

Abstract Bioactive microspheres coated with acellular extracellular matrix (aECM) have received extensive attention in bone tissue engineering. In this work, biomimetic microspheres with different aECM ratios, uniform size and controllable size were prepared easily by blending natural porcine dermal...

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Bibliographic Details
Published in:Regenerative biomaterials 2024, Vol.11
Main Authors: Zhou, Xiaosong, Guo, Min, Wang, Zongliang, Wang, Yu, Zhang, Peibiao
Format: Article
Language:English
Subjects:
Animal models
Biological activity
Biomimetics
Blending
Bone growth
Bone healing
Bones
Cell adhesion
Cell adhesion & migration
Controllability
Electrohydrodynamics
Extracellular matrix
Glycolic acid
Microspheres
Morphology
Polylactide-co-glycolide
Regeneration
Regeneration (physiology)
Scanning electron microscopy
Solidification
Solvent extraction
Spraying
Tissue engineering
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