Mechanism of Xinfeng Capsule in the Treatment of Hypercoagulable State of Ankylosing Spondylitis Based on Data Mining and Network Pharmacology

Background. Ankylosing spondylitis (AS) is a rheumatism that mainly affects the axial bones and joints. Xinfeng capsule (XFC) is a preparation with a remarkable clinical effect that is used in our hospital. And it has definite curative effect and less side effects in the treatment of AS. Objective....

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Bibliographic Details
Published in:	BioMed research international 2022, Vol.2022 (1), p.8796980
Main Authors:	Li, Xu, Liu, Jian, Fang, Yanyan, He, Mingyu, Wang, Fanfan, Han, Qi
Format:	Article
Language:	English
Subjects:	Ankylosing spondylitis Arthritis Associations Bones C-Reactive Protein Care and treatment Cluster analysis Data Mining Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Encyclopedias Enrichment Genomes Herbal medicine Herbs Humans Immunology Inflammation Interleukin 1 Interleukin 17 Joint diseases Kaempferol Laboratories Medicine, Chinese Medicine, Chinese Traditional - methods Modules Molecular docking Molecular Docking Simulation Network analysis Network Pharmacology NF-kappa B - metabolism NF-κB protein Pharmacology Pharmacology, Experimental Protein interaction Proteins Quercetin Random walk Rheumatology Side effects Signal transduction Signaling Software Spondylitis, Ankylosing - drug therapy Spondylitis, Ankylosing - genetics Thrombolytic drugs Traditional Chinese medicine Triptolide Tumor necrosis factor
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