Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis

Bacterial-fungal interactions have important physiologic and medical ramifications, but the mechanisms of these interactions are poorly understood. The gut is host to trillions of microorganisms, and bacterial-fungal interactions are likely to be important. Using a neutropenic mouse model of microbi...

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Bibliographic Details
Published in:PLoS pathogens 2015-08, Vol.11 (8), p.e1005129
Main Authors: Lopez-Medina, Eduardo, Fan, Di, Coughlin, Laura A., Ho, Evi X., Lamont, Iain L., Reimmann, Cornelia, Hooper, Lora V., Koh, Andrew Y.
Format: Article
Language:English
Subjects:
Animals
Bacteriology
Biosynthesis
Candida albicans
Candida albicans - physiology
Cytotoxicity
Farnesol - pharmacology
Female
Gastrointestinal Tract - microbiology
Gene expression
Health aspects
Infections
Iron - metabolism
Male
Mice
Mice, Inbred C3H
Molecular weight
Morphology
Observations
Oligopeptides - antagonists & inhibitors
Oligopeptides - biosynthesis
Pathogenesis
Phenols - antagonists & inhibitors
Proteins
Pseudomonas aeruginosa
Pseudomonas aeruginosa - pathogenicity
Statistical analysis
Thiazoles - antagonists & inhibitors
Virulence
Virulence (Microbiology)
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