Tumor-Associated Macrophages in Tumor Immunity

Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated M2 macrophages. The former typically exerts ant...

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Bibliographic Details
Published in:	Frontiers in immunology 2020-12, Vol.11, p.583084
Main Authors:	Pan, Yueyun, Yu, Yinda, Wang, Xiaojian, Zhang, Ting
Format:	Article
Language:	English
Subjects:	Angiogenesis Animals Antibody-dependent cell-mediated cytotoxicity Bone marrow Cancer therapies Cell growth Chemokines Cytokines Cytotoxicity Drug resistance Glioma Humans Hypoxia Immune response (cell-mediated) Immunity (Disease) Immunology immunosuppression Ligands Lymphocytes T Macrophages Medical prognosis Metabolism Metastases Metastasis Neoplasms - immunology Nitric oxide Reactive oxygen species regulation Roles Stem cells Therapeutic applications Tumor cells Tumor microenvironment Tumor Microenvironment - immunology tumor therapy tumor-associated macrophages Tumor-Associated Macrophages - immunology Tumorigenesis Tumors Vascular endothelial growth factor
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