Nuclear Import of HIV-1

The delivery of the HIV-1 genome into the nucleus is an indispensable step in retroviral infection of non-dividing cells, but the mechanism of HIV-1 nuclear import has been a longstanding debate due to controversial experimental evidence. It was commonly believed that the HIV-1 capsid would need to...

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Bibliographic Details
Published in:Viruses 2021-11, Vol.13 (11), p.2242
Main Authors: Shen, Qi, Wu, Chunxiang, Freniere, Christian, Tripler, Therese N., Xiong, Yong
Format: Article
Language:English
Subjects:
Active Transport, Cell Nucleus
capsid
Capsid - metabolism
Cell Nucleus - metabolism
Cell Nucleus - virology
Cytoplasm
Cytosol
Genomes
HIV
HIV Infections - metabolism
HIV Infections - virology
HIV-1 - metabolism
HIV-1 - physiology
HIV-1 core
Human immunodeficiency virus
Humans
Infections
Integration
Life cycles
nuclear import
nuclear pore
Nuclear Pore - metabolism
nuclear pore complex
Nuclear transport
physiological transport
Reverse Transcription
Review
Uncoating
viral genome
Viral infections
Virus Integration
Virus Uncoating
viruses
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