Enantioselective Reductive Alkenylation of α‐CF 2 H (‐CF 3 ) Amino Halides: Rapid Access to Chiral α‐CF 2 H (‐CF 3 ) Allylamines

The incorporation of fluoroalkyl groups into drug candidates has garnered increasing attention in the pharmaceutical industry due to their ability to modulate lipophilicity, permeability, metabolic stability, and binding affinity. Despite significant advances realized, the means to introducing fluor...

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Bibliographic Details
Published in:Advanced science 2026-01, p.e73986
Main Authors: Liu, Peng, Li, Kuiliang, He, Yan, Jiang, Chen‐Hui, Jin, Ruo‐Xing, Hu, Duo‐Duo, Zhao, Wei‐Cheng, Nie, Xuan, Sun, Shang‐Zheng, Wang, Xi‐Sheng
Format: Article
Language:English
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