The vertebrate Hox gene regulatory network for hindbrain segmentation: Evolution and diversification: Coupling of a Hox gene regulatory network to hindbrain segmentation is an ancient trait originating at the base of vertebrates

Hindbrain development is orchestrated by a vertebrate gene regulatory network that generates segmental patterning along the anterior-posterior axis via Hox genes. Here, we review analyses of vertebrate and invertebrate chordate models that inform upon the evolutionary origin and diversification of t...

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Bibliographic Details
Published in:BioEssays 2016-06, Vol.38 (6), p.526-538
Main Authors: Parker, Hugo J., Bronner, Marianne E., Krumlauf, Robb
Format: Article
Language:English
Subjects:
Animals
Biological Evolution
Body Patterning
brain
Chordata - embryology
Chordata - genetics
Chordata - metabolism
evolution
Gene Expression Regulation, Developmental
Gene Regulatory Networks
Genes, Homeobox - genetics
homeotic genes
Humans
invertebrates
Petromyzon marinus
regulator genes
retinoic acid
Rhombencephalon - embryology
Rhombencephalon - metabolism
vertebrates
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