Occurrence of dyslipidemia in spontaneous intracerebral hemorrhage

Background: Dyslipidemia, mainly hypocholesterolemia is considered to be a risk factor (RF) for spontaneous intracerebral hemorrhage (SICH). The aim of our study was to assess its role in our SICH patients. Methods: In a hospital‐based cross‐section study, laboratory assessments of total cholesterol...

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Published in:European journal of lipid science and technology 2006-05, Vol.108 (5), p.383-388
Main Authors: Herzig, Roman, Vlachová, Ivanka, Mareš, Jan, Křupka, Bohdan, Gabryš, Martin, Vaverková, Helena, Šaňák, Daniel, Schneiderka, Petr, Buřval, Stanislav, Kaňovský, Petr
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cerebrovascular diseases
cholesterol
dyslipidemia
Fat industries
Food industries
Fundamental and applied biological sciences. Psychology
risk factors
spontaneous intracerebral hemorrhage
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Summary:Background: Dyslipidemia, mainly hypocholesterolemia is considered to be a risk factor (RF) for spontaneous intracerebral hemorrhage (SICH). The aim of our study was to assess its role in our SICH patients. Methods: In a hospital‐based cross‐section study, laboratory assessments of total cholesterol (TC), triglycerides (TG), high‐density cholesterol (HDL‐C) and low‐density cholesterol (LDL‐C) plasma levels were performed in 80 SICH patients without vascular malformation and in a control group (CG) of 80 age‐ and sex‐matched patients with low back pain. All patients were treated at the Departments of Neurology and Neurosurgery, University Hospital, Olomouc, Czech Republic. Two‐sample t‐test and Mann‐Whitney test were applied when assessing statistical significance. Results: The following mean lipid plasma levels were found in SICH patients versus CG subjects (in mmol/L): TC, 5.89 vs. 5.48 (p = 0.007); TG, 1.31 vs. 2.10 (p 
ISSN:1438-7697
1438-9312
DOI:10.1002/ejlt.200500285