Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates

Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We comment on factors, such as the presence of additives and the structural nature of the enolate, that influence the observed C‐deuteration and discu...

Full description

Saved in:
Bibliographic Details
Published in:European journal of organic chemistry 2003-02, Vol.2003 (4), p.634-641
Main Authors: Eames, Jason, Coumbarides, Gregory S., Suggate, Michael J., Weerasooriya, Neluka
Format: Article
Language:English
Subjects:
Deuterium
Isotopic labeling
Ketones
Kinetic deuteration
Lithium
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73
cites cdi_FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73
container_end_page 641
container_issue 4
container_start_page 634
container_title European journal of organic chemistry
container_volume 2003
creator Eames, Jason
Coumbarides, Gregory S.
Suggate, Michael J.
Weerasooriya, Neluka
description Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We comment on factors, such as the presence of additives and the structural nature of the enolate, that influence the observed C‐deuteration and discuss the role of the deuterium donor. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
doi_str_mv 10.1002/ejoc.200390103
format article
fullrecord <record><control><sourceid>istex_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_ejoc_200390103</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ark_67375_WNG_C1JTKRBR_D</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73</originalsourceid><addsrcrecordid>eNqFkE1PwkAURSdGExHdup4_UHzT6dcssVQEiSSEqLtJO33FwdoxnQHh3wtCiDtX777knrs4hNwy6DEA_w6XRvV8AC6AAT8jHQZCeBAJON_lgAceE_ztklxZuwQAEUWsQ15GzRqt04vcadNYqhtnqHtHOsOFNhZrVE6vkabeAFcO298aNRXtq62qtaJ5U9JsY45f1pg6d2ivyUWV1xZvjrdL5g_ZPH30JtPhKO1PPMX9kHsckqQSZRwAw0hVGGDklyouyiQokrjkRVSEjClglZ-E3Bc85IqJMCmCkAkV8y7pHWZVa6xtsZJfrf7M261kIPdS5F6KPEnZAeIAfOsat_-0ZTaepn9Z78Bq63BzYvP2Q0Yxj0P5-jyUKRvPn2b3MzngP2ozdcQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Eames, Jason ; Coumbarides, Gregory S. ; Suggate, Michael J. ; Weerasooriya, Neluka</creator><creatorcontrib>Eames, Jason ; Coumbarides, Gregory S. ; Suggate, Michael J. ; Weerasooriya, Neluka</creatorcontrib><description>Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We comment on factors, such as the presence of additives and the structural nature of the enolate, that influence the observed C‐deuteration and discuss the role of the deuterium donor. (© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2003)</description><identifier>ISSN: 1434-193X</identifier><identifier>EISSN: 1099-0690</identifier><identifier>DOI: 10.1002/ejoc.200390103</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>Deuterium ; Isotopic labeling ; Ketones ; Kinetic deuteration ; Lithium</subject><ispartof>European journal of organic chemistry, 2003-02, Vol.2003 (4), p.634-641</ispartof><rights>2002 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73</citedby><cites>FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Eames, Jason</creatorcontrib><creatorcontrib>Coumbarides, Gregory S.</creatorcontrib><creatorcontrib>Suggate, Michael J.</creatorcontrib><creatorcontrib>Weerasooriya, Neluka</creatorcontrib><title>Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates</title><title>European journal of organic chemistry</title><addtitle>Eur. J. Org. Chem</addtitle><description>Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We comment on factors, such as the presence of additives and the structural nature of the enolate, that influence the observed C‐deuteration and discuss the role of the deuterium donor. (© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2003)</description><subject>Deuterium</subject><subject>Isotopic labeling</subject><subject>Ketones</subject><subject>Kinetic deuteration</subject><subject>Lithium</subject><issn>1434-193X</issn><issn>1099-0690</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqFkE1PwkAURSdGExHdup4_UHzT6dcssVQEiSSEqLtJO33FwdoxnQHh3wtCiDtX777knrs4hNwy6DEA_w6XRvV8AC6AAT8jHQZCeBAJON_lgAceE_ztklxZuwQAEUWsQ15GzRqt04vcadNYqhtnqHtHOsOFNhZrVE6vkabeAFcO298aNRXtq62qtaJ5U9JsY45f1pg6d2ivyUWV1xZvjrdL5g_ZPH30JtPhKO1PPMX9kHsckqQSZRwAw0hVGGDklyouyiQokrjkRVSEjClglZ-E3Bc85IqJMCmCkAkV8y7pHWZVa6xtsZJfrf7M261kIPdS5F6KPEnZAeIAfOsat_-0ZTaepn9Z78Bq63BzYvP2Q0Yxj0P5-jyUKRvPn2b3MzngP2ozdcQ</recordid><startdate>200302</startdate><enddate>200302</enddate><creator>Eames, Jason</creator><creator>Coumbarides, Gregory S.</creator><creator>Suggate, Michael J.</creator><creator>Weerasooriya, Neluka</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200302</creationdate><title>Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates</title><author>Eames, Jason ; Coumbarides, Gregory S. ; Suggate, Michael J. ; Weerasooriya, Neluka</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Deuterium</topic><topic>Isotopic labeling</topic><topic>Ketones</topic><topic>Kinetic deuteration</topic><topic>Lithium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eames, Jason</creatorcontrib><creatorcontrib>Coumbarides, Gregory S.</creatorcontrib><creatorcontrib>Suggate, Michael J.</creatorcontrib><creatorcontrib>Weerasooriya, Neluka</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>European journal of organic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eames, Jason</au><au>Coumbarides, Gregory S.</au><au>Suggate, Michael J.</au><au>Weerasooriya, Neluka</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates</atitle><jtitle>European journal of organic chemistry</jtitle><addtitle>Eur. J. Org. Chem</addtitle><date>2003-02</date><risdate>2003</risdate><volume>2003</volume><issue>4</issue><spage>634</spage><epage>641</epage><pages>634-641</pages><issn>1434-193X</issn><eissn>1099-0690</eissn><abstract>Results are reported on the regioselective C‐deuteration of a series of related acyclic and exocyclic enolates derived from substituted aryl ketones. We comment on factors, such as the presence of additives and the structural nature of the enolate, that influence the observed C‐deuteration and discuss the role of the deuterium donor. (© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2003)</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><doi>10.1002/ejoc.200390103</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1434-193X
ispartof European journal of organic chemistry, 2003-02, Vol.2003 (4), p.634-641
issn 1434-193X
1099-0690
language eng
recordid cdi_crossref_primary_10_1002_ejoc_200390103
source Wiley-Blackwell Read & Publish Collection
subjects Deuterium
Isotopic labeling
Ketones
Kinetic deuteration
Lithium
title Investigations into the Regioselective C-Deuteration of Acyclic and Exocyclic Enolates
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T13%3A28%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-istex_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Investigations%20into%20the%20Regioselective%20C-Deuteration%20of%20Acyclic%20and%20Exocyclic%20Enolates&rft.jtitle=European%20journal%20of%20organic%20chemistry&rft.au=Eames,%20Jason&rft.date=2003-02&rft.volume=2003&rft.issue=4&rft.spage=634&rft.epage=641&rft.pages=634-641&rft.issn=1434-193X&rft.eissn=1099-0690&rft_id=info:doi/10.1002/ejoc.200390103&rft_dat=%3Cistex_cross%3Eark_67375_WNG_C1JTKRBR_D%3C/istex_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3253-3088f9d7401e6cfe4e62dc7bd84b87d3b6b511c01f285329353c1958b4519c73%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true