Loading…

Chiral Triphenylprolinol Ligands for the Efficient Catalytic Asymmetric Arylation of Aldehydes

The synthesis of new chiral amino alcohols by Heck arylation of an enecarbamate is described. These compounds were used as chiral ligands for the catalytic asymmetric arylation of aldehydes and can be easily recovered. Chiral, nonracemic diarylmethanols were obtained in high yields and enantioselect...

Full description

Saved in:
Bibliographic Details
Published in:European Journal of Organic Chemistry 2010-07, Vol.2010 (19), p.3696-3703
Main Authors: Moro, Angélica Venturini, Tiekink, Edward R. T., Zukerman-Schpector, Julio, Lüdtke, Diogo S., Correia, Carlos Roque D.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The synthesis of new chiral amino alcohols by Heck arylation of an enecarbamate is described. These compounds were used as chiral ligands for the catalytic asymmetric arylation of aldehydes and can be easily recovered. Chiral, nonracemic diarylmethanols were obtained in high yields and enantioselectivities. The synthesis of several, easily recyclable, new chiral amino alcohols by Heck arylation of an endocyclic enecarbamate is described. These compounds were used aschiral ligands for the catalytic asymmetric arylation of aldehydes. Chiral, nonracemic diarylmethanols were obtained in highyields and enantioselectivities
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201000336