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Chiral Triphenylprolinol Ligands for the Efficient Catalytic Asymmetric Arylation of Aldehydes
The synthesis of new chiral amino alcohols by Heck arylation of an enecarbamate is described. These compounds were used as chiral ligands for the catalytic asymmetric arylation of aldehydes and can be easily recovered. Chiral, nonracemic diarylmethanols were obtained in high yields and enantioselect...
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Published in: | European Journal of Organic Chemistry 2010-07, Vol.2010 (19), p.3696-3703 |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The synthesis of new chiral amino alcohols by Heck arylation of an enecarbamate is described. These compounds were used as chiral ligands for the catalytic asymmetric arylation of aldehydes and can be easily recovered. Chiral, nonracemic diarylmethanols were obtained in high yields and enantioselectivities.
The synthesis of several, easily recyclable, new chiral amino alcohols by Heck arylation of an endocyclic enecarbamate is described. These compounds were used aschiral ligands for the catalytic asymmetric arylation of aldehydes. Chiral, nonracemic diarylmethanols were obtained in highyields and enantioselectivities |
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ISSN: | 1434-193X 1099-0690 |
DOI: | 10.1002/ejoc.201000336 |