A Facile Synthesis of 2,2,4-Trisubstituted-1,2-Dihydroquinolines Catalyzed by Zinc Triflate under Solvent-Free Conditions

An efficient process has been developed for the synthesis of 2,2,4‐trisubstituted‐1,2‐dihydroquinolines in good yields through a simple one‐pot condensation between anilines and ketones in the presence of zinc triflate as a catalyst at room temperature under solvent‐free conditions. An efficient pro...

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Bibliographic Details
Published in:Journal of the Chinese Chemical Society (Taipei) 2008-10, Vol.55 (5), p.1186-1190
Main Authors: Kundu, Dhiman, Kundu, Shrishnu Kumar, Majee, Adinath, Hajra, Alakananda
Format: Article
Language:English
Subjects:
Condensation
Dihydroquinolines
Skraup-Doebner-Von Miller reaction
Solvent-free
Zinc triflate
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Summary:An efficient process has been developed for the synthesis of 2,2,4‐trisubstituted‐1,2‐dihydroquinolines in good yields through a simple one‐pot condensation between anilines and ketones in the presence of zinc triflate as a catalyst at room temperature under solvent‐free conditions. An efficient process has been developed for the synthesis of 2,2,4‐trisubstituted‐1,2‐dihydroquinolines in good yields through a simple one‐pot condensation between anilines and ketones in the presence of zinc triflate as a catalyst at room temperature under solvent‐free
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.200800175