The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has demonstrated that 3CLpros play an indispensable role in viral replication and have been recognized as key targets for prevent...

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Bibliographic Details
Published in:	MedComm (2020) 2022-09, Vol.3 (3), p.e151-n/a
Main Authors:	Hu, Qing, Xiong, Yuan, Zhu, Guang‐Hao, Zhang, Ya‐Ni, Zhang, Yi‐Wen, Huang, Ping, Ge, Guang‐Bo
Format:	Article
Language:	English
Subjects:	3‐chymotrypsin‐like protease (3CLpro) broad‐spectrum anti‐coronavirus agents Coronaviruses COVID-19 Review Reviews SARS‐CoV‐2 Severe acute respiratory syndrome coronavirus 2 β‐coronavirus 3CLpro inhibitor
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