A contribution to the natural history of breast cancer. IV. Lobular carcinoma in situ and its relation to breast cancer

We studied 52 patients with lobular carcinoma in situ (LCIS) of the breast, tissue being available from both breasts in 46 patients. Detailed histological examination of the tissue was combined with specimen radiography. By this technique, six invasive cancers were detected within 2 years of the pri...

Full description

Saved in:
Bibliographic Details
Published in:Archives of Gynecology 1982-06, Vol.231 (3), p.219-226
Main Authors: Tulusan, A H, Egger, H, Schneider, M L, Willgeroth, F
Format: Article
Language:English
Subjects:
Biopsy
Breast - pathology
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Carcinoma in Situ - diagnostic imaging
Carcinoma in Situ - pathology
Female
Humans
Mammography
Time Factors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We studied 52 patients with lobular carcinoma in situ (LCIS) of the breast, tissue being available from both breasts in 46 patients. Detailed histological examination of the tissue was combined with specimen radiography. By this technique, six invasive cancers were detected within 2 years of the primary diagnosis. five of these six carcinomas were clinically occult and were not suspected at specimen radiography. Three other invasive cancers were discovered 4 years, 7 years, and 10 years after diagnosing LCIS. The extent of the LCIS in the primary biopsy was the only feature which gave a guide to the possible presence and location of an occult invasive lesion.
ISSN:0170-9925
1432-0711
DOI:10.1007/BF02110121