A concise stereoselective total synthesis of diplodialide C

An asymmetric total synthesis of diplodialide C has been achieved starting from commercially available homoallylic alcohol. Regioselective opening of the chiral epoxide, cross-metathesis reaction, and Yamaguchi macrolactonization were used as the key steps in this synthesis. Graphical Abstract

Saved in:
Bibliographic Details
Published in:Monatshefte für Chemie 2015-11, Vol.146 (11), p.1921-1926
Main Authors: Pratapareddy, Bommareddy, Sreenivasulu, Reddymasu, Hatti, Islavathu, Venkata Basaveswara Rao, Mandava, Raju, Rudraraju Ramesh
Format: Article
Language:English
Subjects:
Analytical Chemistry
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
Theoretical and Computational Chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An asymmetric total synthesis of diplodialide C has been achieved starting from commercially available homoallylic alcohol. Regioselective opening of the chiral epoxide, cross-metathesis reaction, and Yamaguchi macrolactonization were used as the key steps in this synthesis. Graphical Abstract
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-015-1464-1