New macrocyclic compounds with naphthyridine units for molecular recognition studies of biotin and urea derivatives

Two macrocyclic hosts containing benzenedicarboxamide or pyridinedicarboxamide moieties and two 1,8-naphthyridine units linked by a crown ether like chain, have been synthesized and fully characterized by multinuclear NMR spectroscopy. X-ray diffraction analysis is provided for one of the macrocycle...

Full description

Saved in:
Bibliographic Details
Published in:Journal of inclusion phenomena and macrocyclic chemistry 2015-02, Vol.81 (1-2), p.57-69
Main Authors: Farrán, M. Ángeles, Santa María, Dolores, García, M. Ángeles, Claramunt, Rosa M., Clarkson, Guy J.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Crystallography and Scattering Methods
Food Science
Organic Chemistry
Original Article
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two macrocyclic hosts containing benzenedicarboxamide or pyridinedicarboxamide moieties and two 1,8-naphthyridine units linked by a crown ether like chain, have been synthesized and fully characterized by multinuclear NMR spectroscopy. X-ray diffraction analysis is provided for one of the macrocycles including a DMSO guest molecule. Binding constant determination of both hosts with four ureido derivatives, amongst them (+)-biotin methyl ester, was achieved by means of 1 H NMR titrations.
ISSN:1388-3127
1573-1111
DOI:10.1007/s10847-014-0433-3