Protease-Catalyzed Rational Synthesis of Uric Acid-Lowering Peptides in Non-aqueous Medium

Gout with etiological hyperuricemia deteriorates patient's quality of life, making an urgent need for effective uric acid-lowering drugs. Uric acid-lowering peptides derived from naturally-occurring proteins have great potential therapeutic applications and are found to be rich in aromatic amin...

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Bibliographic Details
Published in:International journal of peptide research and therapeutics 2022-03, Vol.28 (2), Article 61
Main Authors: Huang, Xiao-Ni, Zhang, Yan-Mei, Wen, You, Jiang, Yi, Wang, Cheng-Hua
Format: Article
Language:English
Subjects:
Amino acids
Animal Anatomy
Biochemistry
Biomedical and Life Sciences
Computer applications
Gout
High-performance liquid chromatography
Histidine
Histology
Hyperuricemia
L-Alanine
Leucine
Life Sciences
Molecular Medicine
Morphology
Papain
Peptides
Pharmaceutical Sciences/Technology
Pharmacology/Toxicology
Phenylalanine
Polymer Sciences
Proline
Proteinase
Quality of life
Rheumatism
Therapeutic applications
Tryptophan
Tyrosine
Uric acid
Xanthine oxidase
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