Clinical outcome of nutrition-oriented intervention for primary intestinal lymphangiectasia

• Published in: World journal of pediatrics : WJP 2011-02, Vol.7 (1), p.79-82
• Main Authors: Tang, Qing-Ya, Wen, Jie, Wu, Jiang, Wang, Ying, Cai, Wei
• Format: Article
• Language: English
• Subjects: Brief Report; Critical Care Medicine; Imaging; Intensive; Maternal and Child Health; Medicine; Medicine & Public Health; Pediatric Surgery; Pediatrics; Radiology; Surgery
• ISSN: 1708-8569; 1867-0687
• DOI: 10.1007/s12519-011-0248-x

Background Primary intestinal lymphangiectasia (PIL) is a rare digestive disease and few studies have focused on the therapeutic effect in PIL patients. This study was undertaken to evaluate nutrition-oriented intervention in children with PIL. Methods Four children with PIL were studied. Their medical records were reviewed. Anthropometric measurements and blood tests were performed during a 8–18 month follow-up. Results During hospitalization, the 4 patients were subjected to diet intervention. Parenteral nutrition (PN) support was also given to 3 of them. Clinical symptoms and laboratory parameters of the patients were significantly improved at discharge. After discharge, the patients continued diet control, 2 of whom received intermittent PN support. The mean follow-up duration of the 4 patients was 13 months (range, 8–18 months) and they all kept in a stable condition without symptoms relapse. Weight, height and body mass index for age were normal during the follow-up, while total protein, albumin and immunoglobulin concentrations were still slightly below normal level. Conclusions Nutrition therapy is effective as a valid and safe therapeutic management for PIL patients. No growth retardation was observed in the 4 children after the therapy, but they are still at risk of nutrient malabsorption. Therefore, they need long-term, regular monitoring and intensive nutritional care.