Diastereoselective conjugate addition and cyclopropanation reactions with nitroalkenes derived from ( R)-2,3-isopropylidene glyceraldehyde

In the reactions of functionalized organometallics and of cyclopropanation reagents with chiral nitroalkenes 3 the conjugate addition proceeded with modest to high diastereoselectivity depending on the metal and the substituent R. X-ray analyses showed the nitrocyclopropanes 6, formed with high ster...

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Bibliographic Details
Published in:Tetrahedron letters 1996-08, Vol.37 (35), p.6307-6310
Main Authors: Galley, Guido, Hübner, Jan, Anklam, Sven, Jones, Peter G, Pätzel, Michael
Format: Article
Language:English
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Summary:In the reactions of functionalized organometallics and of cyclopropanation reagents with chiral nitroalkenes 3 the conjugate addition proceeded with modest to high diastereoselectivity depending on the metal and the substituent R. X-ray analyses showed the nitrocyclopropanes 6, formed with high stereoselectivity, to be syn-derivatives. Graphic
ISSN:0040-4039
1873-3581
DOI:10.1016/0040-4039(96)01374-3