A strong static magnetic field inhibits the poly-ADP-ribosylation of proteins in human kidney T1-cells

Exposure of monolayers of human kidney T1-cells to a strong static magnetic field (1.4 T, 30 min at 37°C) reduced the poly-ADP-ribosylation (PADPR) of the total cellular proteins to about 60% of its normal metabolic level. The inhibition was transient and showed dependence on the time of exposure an...

Full description

Saved in:
Bibliographic Details
Published in:Bioelectrochemistry and Bioenergetics 1993-03, Vol.30, p.111-117
Main Authors: Schneeweiss, F.H.A., Xia, F., Sharan, R.N., Feinendegen, L.E.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cell physiology
Effects of physical and chemical agents
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Exposure of monolayers of human kidney T1-cells to a strong static magnetic field (1.4 T, 30 min at 37°C) reduced the poly-ADP-ribosylation (PADPR) of the total cellular proteins to about 60% of its normal metabolic level. The inhibition was transient and showed dependence on the time of exposure and on the strength of the applied static magnetic field. PADPR relaxation kinetics followed a non-monotonous course reaching the metabolic level not earlier than 24 h after the termination of magnetic field interference. It is suggested that the magnetic field interacts with the cellular membrane components affecting the transfer of signals which controls the PADPR of proteins.
ISSN:0302-4598
DOI:10.1016/0302-4598(93)80068-6