Cue-evoked arousal in cocaine users: a study of variance and predictive value

Thirty-six cocaine abusers in treatment and 16 non-using controls were exposed to visual cocaine cues; measurements included changes in skin conductance and a rating of psychological arousal (persisting cocaine thoughts and images during the 24 h following the experiment). The GSI score of the HSCL-...

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Bibliographic Details
Published in:Drug and alcohol dependence 1992-06, Vol.30 (2), p.187-192
Main Authors: Negrete, Juan C., Emil, Sherif
Format: Article
Language:English
Subjects:
Addictive behaviors
Adult
Adult and adolescent clinical studies
Arousal
Biological and medical sciences
cocaine
Cocaine - adverse effects
Conditioning, Classical - drug effects
Cues
Female
Galvanic Skin Response - drug effects
Humans
Male
Medical sciences
Neurologic Examination
prediction
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Substance Abuse Treatment Centers
Substance Withdrawal Syndrome - psychology
Substance Withdrawal Syndrome - rehabilitation
Substance-Related Disorders - psychology
Substance-Related Disorders - rehabilitation
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Summary:Thirty-six cocaine abusers in treatment and 16 non-using controls were exposed to visual cocaine cues; measurements included changes in skin conductance and a rating of psychological arousal (persisting cocaine thoughts and images during the 24 h following the experiment). The GSI score of the HSCL-58 was used as an indicator of psychological distress. Probands showed arousal responses significantly higher than the controls. Skin conductance readings correlated positively with HSCL-58 scores and with severity of craving in the week prior to the trial. Unexpectedly, they correlated negatively with duration of cocaine use and did not vary as a function of the severity of cocaine addiction or the duration of cocaine abstinence prior to the test. Neither cocaine addiction measurements nor arousal responses were found to predict cessation of use (a minimum of 3 months of sustained abstinence) 1 year after the test.
ISSN:0376-8716
1879-0046
DOI:10.1016/0376-8716(92)90025-8