4713 Relationship between endoscopic findings of squamocolumnar junction and corpus gastritis

• Published in: Gastrointestinal endoscopy 2000-04, Vol.51 (4), p.AB211-AB211
• Main Authors: Hamada, Hiroshige, Haruma, Ken, Mihara, Mitsuhiro, Kamada, Tomoari, Kido, Soichiro, Hattori, Nobuaki, Manabe, Noriaki, Kitadai, Yasuhiko, Tanaka, Shinji, Yoshihara, Masaharu, Sumii, Koji, Kajiyama, Goro
• Format: Article
• Language: English
• ISSN: 0016-5107; 1097-6779
• DOI: 10.1016/S0016-5107(00)14560-2

Background and Aims: Although recent studies indicate that the cardia is frequently involved as part of a pangastritis related to Helicobacter pylori(H. pylori) infection, relationship between gastritis, carditis, and endoscopic appearance of squamocolumnar junction (SCJ) has not been studied. The aim of this prospective study was to evaluate the relationship between endoscopic findings of SCJ, H. pyloriinfection, and corpus gastritis in patients without esophagitis. Methods: One hundred and forty-six consecutive patients (mean age:49.1, Male/Female=131/15) without esophagitis were enrolled into the study. Endoscopic findings of SCJ was classified into three categories by one observer: (a) Type A: the junction were straight and not waved; (b) Type B: waved shape and edge of squamous mucosa not colored white; (c) Type C: edge of squamous mucosa colored white and sometimes elevated. Two biopsy specimens were taken from the greater curvature of antrum and corpus. H. pyloriinfection was evaluated by Giemsa staining and serum IgG antibodies. Histological severity of inflammation and glandular atrophy were assessed according to the Updated Sydney system. Results: Thirty eight patients (25%) were classified as Type A, 36 patients (25%) as Type B, and 72 patients (49%) as Type C. Table showed relationship between endoscopic findings, prevalence of H. pylori, and gastritis scores. Conclusions: Endoscopic findings of SCJ were closely associated with the status of H. pyloriinfection and corpus gastritis.