Multiresidue analysis of seventeen pesticides in wine by gas chromatography with mass-selective detection

• Published in: Journal of Chromatography A 2000-06, Vol.882 (1), p.205-212
• Main Authors: Soleas, George J, Yan, Joe, Hom, Kirby, Goldberg, David M
• Format: Article
• Language: English
• Subjects: Gas Chromatography-Mass Spectrometry - methods; Pesticide Residues - analysis; Pesticides; Reproducibility of Results; Sensitivity and Specificity; Wine - analysis
• ISSN: 0021-9673
• DOI: 10.1016/S0021-9673(00)00254-5

We have developed a multiresidue method permitting the simultaneous quantitation of 17 pesticides in wine: dicloran, dimethoate, diazinon, chlorpyrifos-methyl, vinclozolin, carbaryl, methiocarb, dichlofluanid, parathion-ethyl, triadimefon, procymidone, myclobutanil, iprodione, imidan, dicofol, phosalone and azinphos-methyl. Solid-phase extraction of 0.5 ml of wine sample is followed by direct injection of 1 μl of the eluent onto a DB-5 MS gas chromatographic column followed by mass-selective detection using one target and two qualifier ions for each pesticide. The extraction and injection steps are carried out with automatic instrumentation. Good resolution of all compounds was achieved with a run-time approximating 23 min. Detection and quantitation limits were around 2 μg/l and 10 μg/l, respectively, with linear calibration curves up to 3 mg/l for most constituents. Recovery in half the compounds was >90%, and >80% in most of the remainder. Imprecision (relative standard deviation) was