Practical synthesis of both enantiomers of protected 4-oxopipecolic acid

A new synthesis of both enantiomers of protected 4-oxopipecolic acid was achieved in six steps via 1,3-dipolar cycloaddition of C-ethoxycarbonyl N-(1 R)-phenylethylnitrone to but-3-en-1-ol. Graphic

Saved in:
Bibliographic Details
Published in:Tetrahedron 2001-06, Vol.57 (23), p.4995-4998
Main Authors: Machetti, Fabrizio, Cordero, Franca M, De Sarlo, Francesco, Brandi, Alberto
Format: Article
Language:English
Subjects:
amino acid
cycloaddition
nitrone
oxopipecolic acid
rearrangement
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new synthesis of both enantiomers of protected 4-oxopipecolic acid was achieved in six steps via 1,3-dipolar cycloaddition of C-ethoxycarbonyl N-(1 R)-phenylethylnitrone to but-3-en-1-ol. Graphic
ISSN:0040-4020
1464-5416
DOI:10.1016/S0040-4020(01)00429-X