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Recurrent Pneumonia Due to Bronchial Carcinoid Tumour in a Young Patient: The Role of 111In-Pentetreotide in Imaging Studies

Bronchial carcinoid tumors are an uncommon cause of recurrent pneumonia in young patients. Diagnosis is determined from imaging studies, bronchoscopy, and histological confirmation, and treatment is generally surgical. Two cases are reviewed in order to examine the value of 111In-DTPA-Phe-octreotide...

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Bibliographic Details
Published in:Archivos de bronconeumología (English ed.) 2015-03, Vol.51 (3), p.e16-e18
Main Authors: García-Talavera, Paloma, López-Pedreira, María Rosa, Udaondo, Marian, Matilla, José María, Villanueva, Juan Gabriel, Borrego, Henar
Format: Article
Language:English
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Summary:Bronchial carcinoid tumors are an uncommon cause of recurrent pneumonia in young patients. Diagnosis is determined from imaging studies, bronchoscopy, and histological confirmation, and treatment is generally surgical. Two cases are reviewed in order to examine the value of 111In-DTPA-Phe-octreotide (111In-pentetreotide) scintigraphy in the pre-surgical evaluation of these patients. After a suspicious area was observed in other tests (standard X-ray, CT), a neuroendocrine tumor was diagnosed using this technique and the presence of regional or distant disease was ruled out. Comparison with the less valuable 18F-FDG PET (carried out in one of the cases) highlights the usefulness of SPECT-CT, which performs notably better in terms of the localization and characterization of findings. Los tumores carcinoides bronquiales son una causa infrecuente de neumonías de repetición en pacientes jóvenes. El diagnóstico se obtiene mediante pruebas de imagen, broncoscopia y confirmación histológica, y el tratamiento es fundamentalmente quirúrgico. Mediante la presentación de 2 casos, revisamos la utilidad de la gammagrafía con 111In-DTPA-Phe-octreotide (111In-pentetreotida) en la valoración de estos pacientes antes de la cirugía, apoyando el diagnóstico de tumor neuroendocrino ante una imagen sospechosa en otras pruebas (radiografía simple, TC) y descartando enfermedad regional o a distancia. Frente al reducido valor de la PET con 18F-FDG (realizada en uno de los casos), se destaca el papel de la SPECT-TC, que mejora notablemente la localización y la caracterización de los hallazgos.
ISSN:1579-2129
1579-2129
DOI:10.1016/j.arbr.2014.12.022