Epicardial fat thickness correlates with coronary in-stent restenosis in patients with acute myocardial infarction

• Published in: Clínica e investigación en arteriosclerosis (Internet, English ed.) English ed.), 2019-03, Vol.31 (2), p.49-55
• Main Authors: Cabrera-Rego, Julio O., Escobar-Torres, Raúl A., Parra-Jiménez, Juan D., Valiente-Mustelier, Juan
• Format: Article
• Language: English
• Subjects: Acute myocardial infarction; Bare metal stent; Epicardial fat; Grasa epicárdica; Infarto agudo de miocardio; Reestenosis; Restenosis; Stent metálico convencional
• ISSN: 2529-9123; 2529-9123
• DOI: 10.1016/j.artere.2019.03.002

To determine the relation between epicardial fat thickness and coronary in-stent restenosis in patients with acute myocardial infarction and percutaneous coronary intervention. A prospective study was conducted, which included 129 patients (67.3% male, mean age 62.9±10 years) with ST segment elevation acute myocardial infarction undergoing primary percutaneous coronary intervention with bare metal stent. Patients were divided in two groups according to the presence (n=21) or not (n=108) of in-stent restenosis during one year follow-up. Epicardial fat was significantly thicker in patients with coronary in-stent restenosis (5.51±1.6 vs 4.14±2.0mm, p=0.006). A proportionally and significantly thicker epicardial fat was found according to the increase in coronary disease severity (3.3±0.9mm vs 4.3±1.8mm vs 4.7±2.3mm vs 6.7±2.2mm, for type A, B1, B2 and C lesions, respectively, p=0.001) and number of vessels (3.07±1.2mm vs 4.92±1.8mm vs 5.43±2.2mm, for one, two and three vessels disease, respectively, p