Insulin-like growth factor binding proteins 4-6

Insulin-like growth factor binding proteins (IGFBPs) 4-6 have important roles as modulators of IGF actions. IGFBP-4 and IGFBP-6 predominantly inhibit IGF actions, whereas IGFBP-5 may enhance these actions under some circumstances. IGFBP-6 is unique among the IGFBPs for its marked IGF-II binding pref...

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Bibliographic Details
Published in:Baillière's best practice & research. Clinical endocrinology & metabolism 2015-10, Vol.29 (5), p.713-722
Main Author: Bach, Leon A.
Format: Article
Language:English
Subjects:
binding protein
cellular action
Endocrinology & Metabolism
Humans
insulin-like growth factor
Insulin-Like Growth Factor Binding Proteins - blood
Insulin-Like Growth Factor Binding Proteins - metabolism
protein structure
regulation
Signal Transduction
Somatomedins - metabolism
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