Aptamer-functionalized biomimetic supramolecular nanozyme constructed by dipeptide, glutaraldehyde and hemin and its excellent sensing performances for tetrodotoxin

Bioinspired nanozymes hold promise for simulating natural processes and creating optimized functional systems, but their application is hindered by limited catalytic activity and selectivity. These challenges can be addressed by reconstructing enzymatic active sites to enhance catalytic efficiency a...

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Bibliographic Details
Published in:Biosensors & bioelectronics 2025-09, Vol.283, p.117524, Article 117524
Main Authors: Ma, Hongchao, Ma, Xifeng, Dong, Tiantian, Bian, Xinyu, Zhang, Xiaokang, Wei, Yanhui
Format: Article
Language:English
Subjects:
active sites
Aptamer
Aptamers, Nucleotide - chemistry
Biomimetic Materials - chemistry
Biomimetics
Biosensing Techniques - methods
biosensors
Catalysis
catalytic activity
detection limit
dipeptides
Dipeptides - chemistry
Diphenylalanine
Glutaral - chemistry
glutaraldehyde
Hemin
Hemin - chemistry
Limit of Detection
mobile telephones
Nanostructures - chemistry
oligonucleotides
oxidation
Peptide-based nanozyme
Phenylalanine - analogs & derivatives
Phenylalanine - chemistry
tetrodotoxin
Tetrodotoxin - analysis
Tetrodotoxin - chemistry
Tetrodotoxin - isolation & purification
TTX detection
ultraviolet-visible spectroscopy
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