63. Resting state cortical electroencephalographic rhythms in acute stroke patients

• Published in: Clinical neurophysiology 2013-11, Vol.124 (11), p.e203-e203
• Main Authors: Infarinato, F, Percio, C. Del, Lizio, R, Sale, P, Franceschini, M, Lombardi, V, Orzi, F, Rossini, P.M, Babiloni, C
• Format: Article
• Language: English
• Subjects: Neurology
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2013.06.090

Patients suffering from Alzheimer’s disease, Parkinson disease with dementia, and diffuse cerebrovascular dementia show different features of cortical sources of resting state electroencephalographic (EEG) rhythms (Babiloni et al., 2004, 2011). Here, we tested the hypothesis that stroke patients are characterized by peculiar abnormalities of these rhythms. Resting state eyes-closed EEG data were recorded in 29 acute stroke, 29 Alzheimer’s disease, 29 mild cognitive impairment patients, and 29 cognitively intact elderly subjects. Stroke patients were age matched with the other groups, they showed a mild cognitive decline. EEG recordings were performed from the 20th to 30th days from the first ischemic or hemorrhagic acute event. LORETA was used for source estimation. Compared to the other groups, the stroke patients were characterized by a greater power of widespread cortical sources of delta (1–4 Hz) and theta (4–8 Hz) rhythms ( p < 0.05). Abnormal cortical sources of delta and theta rhythms reflect the effects of stroke on cortical neural synchronization. The present study motivates future research evaluating the clinical value of delta sources for the prediction of the patients’ recovery and possible cognitive symptoms.