Vitamin C deficiency and risk of metabolic complications among adults with chronic respiratory diseases: A case–control study

Chronic respiratory disease (CRD) is an airflow limitation that represents a wide array of serious diseases. The aim of this study is to examine the influence of vitamin C deficiency on metabolic health-related quality in individuals with and without chronic respiratory disease in the Gaza Strip. A...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nutrition ESPEN 2021-06, Vol.43, p.448-455
Main Authors: Abuhajar, Sahar M., Taleb, Mahmoud H., Ellulu, Mohammed S.
Format: Article
Language:English
Subjects:
Adult
Antioxidant
Ascorbic Acid
Ascorbic Acid Deficiency - complications
Ascorbic Acid Deficiency - epidemiology
Bronchial asthma
C-Reactive Protein
Case-Control Studies
Chronic obstructive pulmonary disease
Chronic respiratory diseases
Gaza
Humans
Israel
Metabolic complication
Oxidative stress
Palestine
Vitamin C
Waist Circumference
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chronic respiratory disease (CRD) is an airflow limitation that represents a wide array of serious diseases. The aim of this study is to examine the influence of vitamin C deficiency on metabolic health-related quality in individuals with and without chronic respiratory disease in the Gaza Strip. A matched case-control study including 52 cases of CRD and 52 controls of healthy participants were matched by age, sex, body mass index (BMI) and waist circumferences (WC). The study was conducted at the Ministry of Health secondary health-care centers in Gaza strip, Palestine. The biochemical data included Protein Carbonyl (PC), high sensitivity C reactive protein (CRP), vitamin C, fasting blood glucose (FBG) and markers of the lipid profile. By the qualitative estimation of vitamin C consumption, there was a significantly lower consumption of foods that are rich in vitamin C by CRD patients than the matched controls. By comparing the results between both groups, CRD patients had significantly lower plasma concentrations of vitamins C than the control group (18.43 ± 11.93 μgm/ml vs. 24.06 ± 11.19 μgm/ml, P = 0.025), but significantly higher in PC (3.86 ± 4.21 μgm/ml vs. 2.11 ± 0.97 μgm/ml, P = 0.005), CRP (5.98 ± 8.84 mg/l vs. 1.87 ± 1.96 mg/l, P = 0.001), and FBG (102.46 ± 15.09 mg/dl vs. 95.92 ± 10.88 mg/dl, P = 0.017). The results revealed that CRD patients had significantly lower blood oxygen saturation than the control group (96.36 ± 3.81 vs. 98.51 ± 0.75, P 
ISSN:2405-4577
2405-4577
DOI:10.1016/j.clnesp.2021.03.007