Circadian pattern of symptoms onset in patients ≤35years presenting with ST-segment elevation acute myocardial infarction

There are scarce data regarding the circadian pattern of symptoms onset in young patients presenting with acute myocardial infarction (AMI). We explored whether young patients with ST-segment elevation AMI exhibit a circadian variation in symptoms onset. We recruited prospectively 256 consecutive pa...

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Bibliographic Details
Published in:European journal of internal medicine 2015-10, Vol.26 (8), p.607-610
Main Authors: Rallidis, Loukianos S., Triantafyllis, Andreas S., Sakadakis, Eleftherios A., Gialeraki, Argyri, Varounis, Christos, Rallidi, Maria, Tsirebolos, Georgios, Liakos, Georgios, Dagres, Nikolaos, Lekakis, Jonh
Format: Article
Language:English
Subjects:
Circadian variation
Premature myocardial infarction
Smoking
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Summary:There are scarce data regarding the circadian pattern of symptoms onset in young patients presenting with acute myocardial infarction (AMI). We explored whether young patients with ST-segment elevation AMI exhibit a circadian variation in symptoms onset. We recruited prospectively 256 consecutive patients who had survived their first ST-segment elevation AMI ≤35years of age. Patients were categorized into 4 groups by 6-h intervals over 24h. In 49 patients (19.1%) the clinical presentation of AMI was atypical. The symptoms onset was as follows: 00:01 to 06:00, 19.1%, 06:01 to 12:00, 32.4%; 12:01 to 18:00, 28.1%; and 18:01 to 24:00, 20.3%. There was a significant association between the time of day and the likelihood of symptoms onset (Rayleigh test, p
ISSN:0953-6205
1879-0828
DOI:10.1016/j.ejim.2015.05.014