Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases

Regioselective syntheses of glycosides using modern chemical methods suffer from the need to invoke multiple steps of protection and deprotection, and even then product mixtures may occur. Discovering and tuning by mutagenesis glycosyltransferases (GTs) with considerable substrate promiscuity is an...

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Bibliographic Details
Published in:Green synthesis and catalysis 2021-02, Vol.2 (1), p.45-53
Main Authors: Li, Jiao, Qu, Ge, Shang, Na, Chen, Peng, Men, Yan, Liu, Weidong, Mei, Zelong, Sun, Yuanxia, Sun, Zhoutong
Format: Article
Language:English
Subjects:
Directed evolution
Flavonoids
Glucosylation
Glycosyltransferase
Rational design
Regioselectivity
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