Sex Difference in Chest Pain After Implantation of Newer Generation Coronary Drug-Eluting Stents

• Published in: JACC. Cardiovascular interventions 2016-03, Vol.9 (6), p.553-561
• Main Authors: Kok, Marlies M., MD, van der Heijden, Liefke C., MD, Sen, Hanim, MD, PhD, Danse, Peter W., MD, PhD, Löwik, Marije M., PhD, Anthonio, Rutger L., MD, PhD, Louwerenburg, J. (Hans) W., MD, de Man, Frits H.A.F., MD, PhD, Linssen, Gerard C.M., MD, PhD, IJzerman, Maarten J., PhD, Doggen, Carine J.M., PhD, Maas, Angela H.E.M., MD, PhD, Mehran, Roxana, MD, von Birgelen, Clemens, MD, PhD
• Format: Article
• Language: English
• Subjects: Cardiovascular; chest pain; newer generation drug-eluting stent(s); percutaneous coronary intervention; randomized clinical trial; second-generation drug-eluting stent(s); sex analysis
• ISSN: 1936-8798
• DOI: 10.1016/j.jcin.2015.10.043

Abstract Objectives The authors sought to assess sex differences in chest pain after percutaneous coronary intervention (PCI) with newer generation drug-eluting stents (DES). Background Sex-based data on chest pain after PCI with DES are scarce. Methods The authors performed a patient-level pooled analysis of the TWENTE and DUTCH PEERS randomized trials, in which patients were treated with newer generation permanent polymer-coated DES. At 1 and 2 years, clinical follow-up was available in 99.8% and patient-reported chest pain data in 94.1% and 93.6%, respectively. Results Among all 3,202 patients, the 871 (27.2%) women were older (67.5 ± 10.2 years vs. 62.8 ± 10.6 years; p