96. Screening for Mullerian Anomalies in Patients with known Renal Anomalies

• Published in: Journal of pediatric & adolescent gynecology 2023-04, Vol.36 (2), p.214-215
• Main Authors: Rosenberg, Sofie L., Beaty, Laurel, Hutchens, Kendra, Alaniz, Veronica I.
• Format: Article
• Language: English
• ISSN: 1083-3188; 1873-4332
• DOI: 10.1016/j.jpag.2023.01.239

The association between Mullerian anomalies (MAs) and renal anomalies (RAs) is well documented. Of women diagnosed with RAs, 20-40% also have a coexistent Mullerian anomaly. Despite this correlation, no formal guidelines exist to direct MA screening practices for female patients with known renal anomalies. The lack of universal guidelines may lead to greater delays in the detection and diagnosis of MAs in this patient population. The purpose of this study is to establish a baseline rate of pelvic imaging practices among female patients with renal anomalies at a tertiary children's hospital. A retrospective chart review was performed on female patients aged 0-25 with congenital renal anomalies who presented to a tertiary children's hospital between January 2015 and June 2022. Descriptive statistics were calculated for continuous variables using means and ranges. A total of 212 patients met inclusion criteria. The most common congenital renal anomaly diagnoses included multicystic kidney disease (61, 28.8%), renal agenesis (39, 18.4%), and renal dysplasia/hypoplasia (35, 16.5%). Among patients who received a post-natal diagnosis, the average age of diagnosis was 8.6 years (range 0-20). Within this patient population 34% (72) received any pelvic imaging that evaluated uterine anatomy. Only one imaging study was ordered with the indication of screening for a Mullerian anomaly. The remaining studies were ordered for other indications such as pelvic pain, abnormal bleeding, and renal surveillance. These studies were ordered by the emergency department (22, 30.6%), gynecology (16, 22.2%), primary care (14, 19.4%), urology (4, 5.6%), and other subspecialties (15, 20.8%). Patients most commonly received pelvic ultrasounds (57, 79.2%) and ultrasound imaging identified uterine or vaginal anomalies in 17 patients (29.8%). These findings suggest that most patients with renal anomalies have not undergone pelvic imaging to evaluate for Mullerian anomalies. Almost all imaging studies that evaluated reproductive anatomy were ordered for indications other than screening for Mullerian anomalies. Education and screening guidelines are being planned with the goal of increasing screening for Mullerian anomalies in patients with known renal anomalies. Supporting Figures or Tables https://www.abstractscorecard.com/uploads/Tasks/upload/19245/RGXGDRUQ-1380844-1-ANY.docx https://www.abstractscorecard.com/uploads/Tasks/upload/19245/RGXGDRUQ-1380844-2-ANY.docx