FeTiO3 nanohexagons based electrochemical sensor for the detection of dopamine in presence of uric acid

• Published in: Materials chemistry and physics 2019-05, Vol.233, p.319-328
• Main Authors: Aparna, T.K., Sivasubramanian, R.
• Format: Article
• Language: English
• Subjects: Dopamine; Electrochemical sensor; FeTiO3 nanohexagons; Perovskite; Uric acid
• ISSN: 0254-0584; 1879-3312
• DOI: 10.1016/j.matchemphys.2019.05.073

A simple hydrothermal synthesis of FeTiO3 nanohexagons and its application in the detection of dopamine (DA) in presence of uric acid (UA) was reported. The FeTiO3 nanohexagons were synthesized through a facile hydrothermal route using urea as the stabilizing agent. The material was characterized with transmission electron microscope (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FTIR) spectroscopy. The FeTiO3 modified glassy carbon electrode was further employed for detection of DA and UA. The sensor showed an excellent performance in terms of detection limit, linear range and sensitivity. For DA, the detection limit was deduced as 1.3 nM with a sensitivity of 1.56 μA μM−1 cm−2 and linearity was observed in the range from 1 μM to 90 μM and 110 μM–350 μM. And for UA, the detection limit and linear range was estimated as 30 nM and 1 μM–150 μM and 200 μM–500 μM. The catalytic rate constant for dopamine oxidation on FeTiO3 was estimated as 2.946 × 103 M−1 s−1. Further, the simultaneous detection of DA and UA was demonstrated on FeTiO3/GCE. The practical applicability of the sensor was tested in serum and urine biological samples. Display Omitted •FeTiO3 perovskite nanostructure was employed for the detection of DA.•Enhanced performance due to multiple redox and oxygen deficient sites.•Detection limit in Sub-micromolar range was achieved.•Selective and simultaneous detection of DA and UA was demonstrated.