Bioinspired design of mesoporous silica complex based on active site of carbonic anhydrase

•We synthesized an artificial catalyst based on the active site of carbonic anhydrase (CA).•The metal-complex showed the ability of enhanced CO2 hydration under ambient condition.•The artificial hydrophobic environment was added to the metal-complex.•The hydrophobic effect improved the ability of CO...

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Bibliographic Details
Published in:Journal of molecular catalysis. A, Chemical Chemical, 2014-08, Vol.390, p.105-113
Main Authors: Sahoo, Prakash C., Jang, Young Nam, Suh, Yong Jae, Lee, Seung Woo
Format: Article
Language:English
Subjects:
Biomimetic CO2 sequestration
Carbon dioxide
Catalysis
Chemistry
CO2 hydration
Colloidal state and disperse state
Exact sciences and technology
General and physical chemistry
In vitro crystallization
Mesoporous silica
Porous materials
Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry
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Summary:•We synthesized an artificial catalyst based on the active site of carbonic anhydrase (CA).•The metal-complex showed the ability of enhanced CO2 hydration under ambient condition.•The artificial hydrophobic environment was added to the metal-complex.•The hydrophobic effect improved the ability of CO2 hydration. We present the facile synthesis of Co and Zn biomimetic complexes inside the mesoporous silica (MS) nano cages. These biomimetic complexes (Co–Im@MS and Zn–Im@MS) mimicked the active site of carbonic anhydrase and showed an enhanced catalytic activity in CO2 hydration. Furthermore, a partial hydrophobic environment imposed by hexadecanol functionalization, enhanced the activity of Co–Im@MS and Zn–Im@MS. The hexadecanol functionalized Co–Im@MS and Zn–Im@MS, therefore, represent true models for carbonic anhydrase, in which the complexes catalyses CO2 hydration. The hexadecanol moiety could be suggested as a positive modulator for the enhancement of CO2 hydration. BET, FE-SEM, FE-TEM, 29Si NMR, FTIR, UV–vis DRS, XRD and XPS were applied for the characterization of the functionalized supports and the biomimetic catalysts. The synthesized catalysts were applied to in vitro CaCO3 crystallization and resulted in the morphologically altered CaCO3. We believe that this study will facilitate the development of optimized model systems in the field of biomimetic catalysis.
ISSN:1381-1169
1873-314X
DOI:10.1016/j.molcata.2014.03.013