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Solubility and thermodynamics of ferulic acid in different neat solvents: Measurement, correlation and molecular interactions

In the present investigation, the solubility of a bioactive compound ferulic acid (FA) in various neat solvents namely “water, methanol, ethanol, isopropanol (IPA), ethylene glycol (EG), propylene glycol (PG), 1-butanol, 2-butanol, ethyl acetate (EA), dimethyl sulfoxide (DMSO), polyethylene glycol-4...

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Bibliographic Details
Published in:Journal of molecular liquids 2017-06, Vol.236, p.144-150
Main Authors: Shakeel, Faiyaz, Salem-Bekhit, Mounir M., Haq, Nazrul, Siddiqui, Nasir A.
Format: Article
Language:English
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Summary:In the present investigation, the solubility of a bioactive compound ferulic acid (FA) in various neat solvents namely “water, methanol, ethanol, isopropanol (IPA), ethylene glycol (EG), propylene glycol (PG), 1-butanol, 2-butanol, ethyl acetate (EA), dimethyl sulfoxide (DMSO), polyethylene glycol-400 (PEG-400) and Transcutol®” was measured, correlated and evaluated for molecular interactions. The solubilities of FA in mole fraction were measured at temperatures “T=298.2K to 318.2K” and pressure “p=0.1MPa”. The experimental solubilities of FA were correlated with “Van't Hoff and Apelblat models” with root mean square deviation values of
ISSN:0167-7322
1873-3166
DOI:10.1016/j.molliq.2017.04.014