AMERICAN TEGUMENTARY LEISHMANIASIS: REPORT OF A CASE

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2020-09, Vol.130 (3), p.e201-e201
• Main Authors: ZIGMUNDO, GISELE CORRêA DE OLIVEIRA, CRUZ, KARINA PEREIRA DA, HERPICH, TIAGO LUíS, KUHL, GABRIEL, RIVERO, LUIS FERNANDO DA ROSA, MARTINS, MARCO ANTONIO TREVIZANI, MARTINS, MANOELA DOMINGUES
• Format: Article
• Language: English
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2020.04.433

American tegumentary leishmaniasis (ATL) is the most common form of leishmaniasis that promote cutaneous and mucosal lesions. It represents a parasitic disease caused by protozoa of the genus Leishmania sp., transmitted by the bite of naturally infected sandflies of the genus Lutzomyia. A 51-year-old male patient attended the medical service reporting weight loss, hoarseness, hemoptysis, dysphagia, and dyspnea. Clinical and videolaryngoscopic examination revealed an ulcerated, granulomatous, friable lesion, extending to the soft palate, nasopharynx, and supraglottic larynx. Patient reported 1-year evolution, with no response to previous antifungal treatment. In medical history, patient described having had leishmaniasis 30 years ago. The hypotheses of diagnosis were fungal/parasitic infection, malignant neoplasm, and autoimmune disease. Incisional biopsy was performed, with the presence of extra and intracellular Leishmania parasites in the microscopic analysis. Fungi and bacteria analysis were negative. Treatment with liposomal Amphotericin B was proposed; however, patient refused treatment and requested hospital discharge.