PERIPHERAL ODONTOGENIC MYXOMA VS INFLAMMATORY MYOFIBROBLASTIC TUMOR? REPORT OF AN UNUSUAL CASE OF MYXOID LESION

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2024-06, Vol.137 (6), p.e226-e226
• Main Authors: de MAGALHÃES, Vitórya Carvalho Pádua, MELO, Thayna, PERALTA, Felipe, KITAKAWA, Dárcio, JÚNIOR, Lineu Perrone, de CARVALHO, Luis Felipe das Chagas e Silva
• Format: Article
• Language: English
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.12.382

Odontogenic myxoma is characterized by stellate and fusiform cells scattered within an abundant myxoid extracellular matrix. In contrast, the inflammatory myofibroblastic tumor consists of spindle cells in association with inflammatory cells. This paper aims to present an unusual case of a myxoid lesion in the maxilla. A 45-year-old female patient presented with a nodular lesion on the maxilla, measuring 5 cm at its largest extent. The lesion was reddish in color, had an ulcerated surface, and caused painful symptoms. An incisional biopsy was performed, revealing morphological features of fusiform and stellate cells interspersed within a loose stroma. Additionally, areas containing inflammatory cells were observed. Immunohistochemical staining showed that spindle and stellate cells were positive for calponin, HHF-35, and α-SMA but negative for S-100, CD34, CD68, desmin, and H-Caldesmon. The histological diagnosis was a myxoid lesion in the maxilla. This case underscores the diagnostic challenge posed by spindle cell lesions for oral pathologists.