Temporal Changes in a Novel Metric of Physical Activity Tracking (Personal Activity Intelligence) and Mortality: The HUNT Study, Norway

• Published in: Progress in cardiovascular diseases 2019-03, Vol.62 (2), p.186-192
• Main Authors: Kieffer, Sophie K., Croci, Ilaria, Wisløff, Ulrik, Nauman, Javaid
• Format: Article
• Language: English
• Subjects: Activity tracking; Cardiovascular disease mortality; Physical activity promotion; Prevention
• ISSN: 0033-0620; 1532-8643
• DOI: 10.1016/j.pcad.2018.09.002

Personal Activity Intelligence (PAI) is a novel activity metric that translates heart rate variations during exercise into a weekly score. Weekly PAI scores assessed at a single point in time were found to associate with lower risk of premature cardiovascular disease (CVD) mortality in the general healthy population. However, to date, the associations between long-term longitudinal changes in weekly PAI scores and mortality have not been explored. The aim of the present study was to prospectively examine the association between change in weekly PAI scores estimated 10 years apart, and risk of mortality from CVD and all-causes. We performed a prospective cohort study of 11,870 men and 13,010 women without known CVD in Norway. By using data from the Nord-Trøndelag Health Study (HUNT), PAI was estimated twice, ten years apart (HUNT1 1984-86 and HUNT2 1995-97). Mortality was followed-up until December 31, 2015. Adjusted hazard ratios (AHR) and 95% confidence intervals (CI) for death from CVD and all-causes related to temporal changes in PAI were estimated using Cox regression analyses. During a mean (SD) of 18 (4) years of follow-up, there were 4782 deaths, including 1560 deaths caused by CVD. Multi-adjusted analyses demonstrated that participants achieving a score of ≥100 PAI at both time points had 32% lower risk of CVD mortality (AHR 0.68; CI: 0.54–0.86) for CVD mortality and 20% lower risk of all-cause mortality (AHR 0.80; CI: 71–0.91) compared with participants obtaining