Interleukin 32, inflammation and cancer

Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer development. IL-32 gene consists of eight small exons, and IL-32 mRNA has nine alternative spliced isoforms, and was thought to be secreted because it contains an internal signal sequence and lacks a transmembrane region....

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Bibliographic Details
Published in:Pharmacology & therapeutics (Oxford) 2017-06, Vol.174, p.127-137
Main Authors: Hong, Jin Tae, Son, Dong Ju, Lee, Chong Kil, Yoon, Do-Young, Lee, Dong Hun, Park, Mi Hee
Format: Article
Language:English
Subjects:
Animals
Anti-Inflammatory Agents - pharmacology
Antineoplastic Agents - pharmacology
Drug Design
Humans
Inflammation - immunology
Inflammation - pathology
Inflammation - therapy
Interleukins - genetics
Interleukins - immunology
Interleukins - metabolism
Molecular Targeted Therapy
Neoplasms - immunology
Neoplasms - pathology
Neoplasms - therapy
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