105 Body mass index and mean arterial pressure are increased in nulliparous with late preeclampsia

• Published in: Pregnancy hypertension 2016-07, Vol.6 (3), p.229-230
• Main Authors: Alves, Júlio Augusto Gurgel, E Moura, Sammya Bezerra Maia Holanda, Sousa, Paulo Cesar Praciano, Da Silva Costa, Fabricio
• Format: Article
• Language: English
• Subjects: Cardiovascular; Obstetrics and Gynecology
• ISSN: 2210-7789
• DOI: 10.1016/j.preghy.2016.08.187

Introduction During the past three decades, numerous clinical, biophysical, and biochemical screening tests have been proposed for the prediction of preeclampsia. Preeclampsia (PE), can be classified according to the timing of disease onset: early-onset PE occurs before the 34th gestational week and late-onset PE occurs in the 34th gestational week or later. Objectives The aim of this study was to analyze which clinical factors would be more prevalent in nulliparous women that developed late onset preeclampsia (PE). Methods Prospective study with singleton pregnancies examined at first trimester or at beginning of second trimester of gestation, presenting consecutively for antenatal care in a tertiary Brazilian hospital. The base-cohort population constituted of 474 nulliparous., including 14 subjects who developed pre-eclampsia (PE) requiring delivery before 34 weeks (early PE) and 41 with late PE, 37 with gestational hypertension, and 382 cases subjects (80%) who were unaffected by PE or gestational hypertension. Maternal history (nulliparity, previous and family history of hypertension), body mass index (BMI), mean arterial pressure (MAP), were recorded in all of the cases. In case-control study, epidemiologic variables were compared between 41 patients with late PE and 82 patients with. The control group‘s patients were chosen between uncomplicated pregnancies subsequently numbered in prenatal care after each late PE case. Data were analyzed using STATA 10 software. P < 0.05 was considered significant. Results BMI and PAM parameters were significantly higher in the group that developed late PE. Other clinical risk factors such as age, smoking, personal or family history of hypertension showed no statistically significant differences between groups.