Monitoring hepatic cysteine dynamics in obesity models with sulfur-substituted hemicyanine-based nanoprobes

Cysteine (Cys) plays pivotal roles in redox homeostasis and metabolic regulation, with its dysregulation implicated in obesity-related hepatic disorders. Here, we developed a sulfur-substituted hemicyanine-based nanoprobe (Cys-NP) for photoacoustic imaging of hepatic Cys dynamics. The Cys-responsive...

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Bibliographic Details
Published in:Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Molecular and biomolecular spectroscopy, 2026-02, Vol.346, p.126965, Article 126965
Main Authors: Qiao, Jing-Jing, Fan, Lu, Zhou, Jie-Li, Wang, Kai
Format: Article
Language:English
Subjects:
Animals
Carbocyanines - chemistry
Cysteine
Cysteine - analysis
Cysteine - metabolism
Diet, High-Fat
Disease Models, Animal
Liver - diagnostic imaging
Liver - metabolism
Male
Mice
Mice, Inbred C57BL
Molecular Probes - chemistry
Nanoparticles - chemistry
Obesity
Obesity - metabolism
Photoacoustic
Serum tests
Sulfur - chemistry
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