‘Warburg effect’ controls tumor growth, bacterial, viral infections and immunity – Genetic deconstruction and therapeutic perspectives

The evolutionary pressure for life transitioning from extended periods of hypoxia to an increasingly oxygenated atmosphere initiated drastic selections for a variety of biochemical pathways supporting the robust life currently present on the planet. First, we discuss how fermentative glycolysis, a p...

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Bibliographic Details
Published in:Seminars in cancer biology 2022-11, Vol.86 (Pt 2), p.334-346
Main Authors: Pouysségur, J., Marchiq, I., Parks, S.K., Durivault, J., Ždralević, M., Vucetic, M.
Format: Article
Language:English
Subjects:
Acidosis
Bacteria
BASIGIN
Cancer
CRISPR-cas9
Fermentative glycolysis
Glycogen
GPI
Immune evasion
Immunity
Lactate
LDHA
LDHB
MCT1
MCT4
OXPHOS
Pathogens
Viruses
Warburg effect
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